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ΠΦΥ -Εκπαίδευση => Αποσπάσματα από τον έντυπο & ηλεκτρονικό τύπο => Μήνυμα ξεκίνησε από: Argirios Argiriou στις 12 Ιουνίου 2014, 10:00:34

Τίτλος: Thyroid Nodules: Is It Time to Turn Off the Ultrasound Machines?
Αποστολή από: Argirios Argiriou στις 12 Ιουνίου 2014, 10:00:34

Radiology.
June 2008, Volume 247, Issue 3, p. 602-604


Thyroid Nodules: Is It Time to Turn Off the US (=ultrasound) Machines?

http://pubs.rsna.org/doi/full/10.1148/radiol.2473072233

Τίτλος: Απ: Thyroid Nodules: Is It Time to Turn Off the Ultrasound Machines?
Αποστολή από: Argirios Argiriou στις 18 Δεκεμβρίου 2016, 00:29:50

Research

Association between screening and the thyroid cancer “epidemic” in South Korea: evidence from a nationwide study

BMJ 2016; 355 doi: http://dx.doi.org/10.1136/bmj.i5745 (Published 30 November 2016)

Cite this as: BMJ 2016;355:i5745


Sohee Park, associate professor1 2, Chang-Mo Oh, associate scientist1, Hyunsoon Cho, assistant professor1 3, Joo Young Lee, postdoctoral fellow1 4, Kyu-Won Jung, senior scientist1, Jae Kwan Jun, chief scientist1 3, Young-Joo Won, senior scientist1 3, Hyun-Joo Kong, data manager1, Kui Son Choi, professor1 3, You Jin Lee, associate scientist5, Jin Soo Lee, chief scientist3 6
Author affiliations
Correspondence to: J S Lee, National Cancer Center Research Institute & Hospital, National Cancer Center, 111, Jungbalsan-ro, Ilsandong-gu, Goyang, Gyeonggi-do 410-769, Republic of Korea jslee@ncc.re.kr

Accepted 21 October 2016

Abstract

Objective To investigate whether screening for thyroid cancer led to the current “epidemic” in South Korea.

Design Review of the medical records of nationally representative samples of patients with a diagnosis of thyroid cancer in 1999, 2005, and 2008.

Setting Sample cases were randomly selected from South Korea’s nationwide cancer registry, using a systematic sampling method after stratification by region.

Participants 5796 patients with thyroid cancer were included (891 in 1999, 2355 in 2005, and 2550 in 2008).

Main outcome measures The primary outcome was age standardised incidence of thyroid cancer and the changes in incidence between 1999 and 2008 according to the methods used to detect tumours (screen detection versus clinical detection versus unspecified).

Results Between 1999 and 2008, the incidence of thyroid cancer increased 6.4-fold (95% confidence interval 4.9-fold to 8.4-fold), from 6.4 (95% confidence interval 6.2 to 6.6) per 100 000 population to 40.7 (40.2 to 41.2) per 100 000 population. Of the increase, 94.4% (34.4 per 100 000 population) were for tumours less than 20 mm, which were detected mainly by screening. 97.1% of the total increase was localised and regional tumours according to the Surveillance, Epidemiology, and End Results (SEER) summary stage. Where cases were clinically detected, 99.9% of the increased incidences (6.4 per 100 000 population) over the same period were tumours less than 20 mm.

Conclusion The current “epidemic” of thyroid cancer in South Korea is due to an increase in the detection of small tumours, most likely as a result of overdetection. Concerted efforts are needed at a national level to reduce unnecessary thyroid ultrasound examinations in the asymptomatic general population.

http://www.bmj.com/content/355/bmj.i5745

Τίτλος: Overdiagnosis and overtreatment of thyroid cancer: A population-based temporal t
Αποστολή από: Argirios Argiriou στις 14 Ιανουαρίου 2020, 23:12:24

Jegerlehner S, Bulliard JL, Aujesky D, et al.
PLoS One. 2017;12(6):e0179387. Published 2017 Jun 14. doi:10.1371/journal.pone.0179387

Overdiagnosis and overtreatment of thyroid cancer: A population-based temporal trend study.

https://www.ncbi.nlm.nih.gov/pmc/articles/PMC5470703/?fbclid=IwAR2gz6DJNBmuJhtmEu_g7PEc2toC4hm2QwvMhJlfPwTRKg_tWBn0pPbzjjM (https://www.ncbi.nlm.nih.gov/pmc/articles/PMC5470703/?fbclid=IwAR2gz6DJNBmuJhtmEu_g7PEc2toC4hm2QwvMhJlfPwTRKg_tWBn0pPbzjjM)