91
Αποσπάσματα από τον έντυπο & ηλεκτρονικό τύπο / Απ: Educational videos from Youtube: Ultrasound.
« Τελευταίο μήνυμα από Argirios Argiriou στις 6 Μαρτίου 2026, 20:26:52 »The Playboy Bunny Sign
Τελευταία μηνύματα
92
Συζητήσεις πάνω σε ιατρικά θέματα / Are glp1 approved for use in Diabetes Mellitus type1?
« Τελευταίο μήνυμα από Argirios Argiriou στις 6 Μαρτίου 2026, 20:11:45 »Έβαλα στο chat gpt την παρακάτω ερώτηση:
- Are glp1 approved for use in Diabetes Mellitus type1?
Και έλαβα την παρακάτω απάντηση:
-
Short answer:
❌ No — GLP-1 receptor agonists are not currently approved for the treatment of Type 1 Diabetes Mellitus (T1DM).
Regulatory approval
Drugs in the GLP-1 receptor agonist class (e.g., semaglutide, liraglutide, dulaglutide) are approved for:
Type 2 diabetes
Obesity / weight management
Some cardiovascular risk reduction indications
However, they are not licensed for glycemic control in Type 1 diabetes.
Regulatory labeling explicitly states that these drugs are not approved for T1DM management, largely because patients with T1DM were excluded from most large randomized trials.
Guideline recommendations
Major guidelines (e.g., ADA) generally state:
Insulin remains the essential therapy in T1DM.
GLP-1 RAs are not recommended as routine treatment for T1DM due to limited safety and efficacy data
Potential concerns include:
Risk of diabetic ketoacidosis
Increased risk of hypoglycemia when combined with insulin
Lack of long-term outcome data in T1DM.
Off-label and research use
There is growing research interest in using GLP-1 agonists as adjunct therapy with insulin in selected T1DM patients.
Studies show possible:
small HbA1c reduction (~0.2%)
weight loss (~3–4 kg)
reduced insulin dose requirements.
Some clinicians may prescribe them off-label, particularly in T1DM patients with:
obesity
insulin resistance
high insulin requirements
But this is not standard practice and requires specialist supervision.
- Are glp1 approved for use in Diabetes Mellitus type1?
Και έλαβα την παρακάτω απάντηση:
-
Short answer:
❌ No — GLP-1 receptor agonists are not currently approved for the treatment of Type 1 Diabetes Mellitus (T1DM).
Regulatory approval
Drugs in the GLP-1 receptor agonist class (e.g., semaglutide, liraglutide, dulaglutide) are approved for:
Type 2 diabetes
Obesity / weight management
Some cardiovascular risk reduction indications
However, they are not licensed for glycemic control in Type 1 diabetes.
Regulatory labeling explicitly states that these drugs are not approved for T1DM management, largely because patients with T1DM were excluded from most large randomized trials.
Guideline recommendations
Major guidelines (e.g., ADA) generally state:
Insulin remains the essential therapy in T1DM.
GLP-1 RAs are not recommended as routine treatment for T1DM due to limited safety and efficacy data
Potential concerns include:
Risk of diabetic ketoacidosis
Increased risk of hypoglycemia when combined with insulin
Lack of long-term outcome data in T1DM.
Off-label and research use
There is growing research interest in using GLP-1 agonists as adjunct therapy with insulin in selected T1DM patients.
Studies show possible:
small HbA1c reduction (~0.2%)
weight loss (~3–4 kg)
reduced insulin dose requirements.
Some clinicians may prescribe them off-label, particularly in T1DM patients with:
obesity
insulin resistance
high insulin requirements
But this is not standard practice and requires specialist supervision.
93
Συζητήσεις πάνω σε ιατρικά θέματα / Are SGLT2 approved for Diabetes Mellitus type 1?
« Τελευταίο μήνυμα από Argirios Argiriou στις 5 Μαρτίου 2026, 20:57:55 »Στις 05/03/2026 έβαλα στο chatgtpt την παρακάτω ερώτηση:
- Are SGLT2 approved for Diabetes Mellitus type 1?
και έλαβα την παρακάτω απάντηση:
- Short answer: No.
Details:
SGLT2 inhibitors are not FDA‑approved or EMA‑approved for Type 1 Diabetes.
They were previously approved in the EU (e.g., dapagliflozin, sotagliflozin) as adjunct therapy for adults with Type 1 diabetes, but these approvals were withdrawn due to increased risk of euglycemic diabetic ketoacidosis (DKA).
Their use in Type 1 Diabetes today is considered off‑label and generally not recommended except in specialized settings with strict monitoring.
- Are SGLT2 approved for Diabetes Mellitus type 1?
και έλαβα την παρακάτω απάντηση:
- Short answer: No.
Details:
SGLT2 inhibitors are not FDA‑approved or EMA‑approved for Type 1 Diabetes.
They were previously approved in the EU (e.g., dapagliflozin, sotagliflozin) as adjunct therapy for adults with Type 1 diabetes, but these approvals were withdrawn due to increased risk of euglycemic diabetic ketoacidosis (DKA).
Their use in Type 1 Diabetes today is considered off‑label and generally not recommended except in specialized settings with strict monitoring.
94
Χαλαρή κουβέντα / Τα 5 πράγματα που πρέπει να έχετε στο κινητό σας για ώρα ανάγκης.
« Τελευταίο μήνυμα από Argirios Argiriou στις 5 Μαρτίου 2026, 16:24:07 »95
Αποσπάσματα από τον έντυπο και ηλεκτρονικό τύπο / Perception of time, as we age.
« Τελευταίο μήνυμα από Argirios Argiriou στις 5 Μαρτίου 2026, 12:17:56 »Perception of time, as we age.
The brain maze
When you’re five years old, a single year represents 20% of your entire life, but at fifty, it accounts for just 2%, which helps explain why time feels like it speeds up as we age.
This idea, often referred to as Janet’s Law, suggests that by the age of twenty, you’ve already lived roughly half of your perceived life.
In other words, a summer holiday at five can feel as long as the entire decade from forty to fifty.
However, this acceleration of time isn’t inevitable—having agency and seeking new experiences can slow it down by creating richer, more lasting memories.
If you live on autopilot, life may feel short and compressed, but if you actively pursue growth and novelty, your eighty years can feel like two hundred.
The brain maze
When you’re five years old, a single year represents 20% of your entire life, but at fifty, it accounts for just 2%, which helps explain why time feels like it speeds up as we age.
This idea, often referred to as Janet’s Law, suggests that by the age of twenty, you’ve already lived roughly half of your perceived life.
In other words, a summer holiday at five can feel as long as the entire decade from forty to fifty.
However, this acceleration of time isn’t inevitable—having agency and seeking new experiences can slow it down by creating richer, more lasting memories.
If you live on autopilot, life may feel short and compressed, but if you actively pursue growth and novelty, your eighty years can feel like two hundred.
96
Συζητήσεις πάνω σε ιατρικά θέματα / Απ: Πόσο καιρό μπορούμε να κρατήσουμε έναν καθετήρα σιλικόνης;
« Τελευταίο μήνυμα από schumifer στις 5 Μαρτίου 2026, 11:13:02 »97
Πολιτική και Κοινωνικά Θέματα / ΔΝΤ: Η παγκόσμια οικονομία «τίθεται εκ νέου σε δοκιμασία» εξαιτίας του πολέμου σ
« Τελευταίο μήνυμα από Argirios Argiriou στις 5 Μαρτίου 2026, 06:49:01 »98
Πολιτική και Κοινωνικά Θέματα / Σκωτία: Νομιμοποίηση της Υγρής Αποτέφρωσης για οικολογικούς λόγους.
« Τελευταίο μήνυμα από Argirios Argiriou στις 4 Μαρτίου 2026, 22:22:29 »99
Αποσπάσματα από τον έντυπο & ηλεκτρονικό τύπο / Απ: Η Υγεία σε Παγκόσμιο επίπεδο. ( planetary health )
« Τελευταίο μήνυμα από Argirios Argiriou στις 4 Μαρτίου 2026, 17:39:13 »100